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Ischaemic stroke in cats: causes, symptoms and prevention

An ischaemic stroke in a cat is a sudden disruption of blood flow to the brain, leaving part of it without enough blood and oxygen. This causes neurological deficits, such as poor coordination, limb weakness, seizures or loss of sight. Stroke is less common in cats than in people or dogs, but it is recognised in veterinary medicine and requires immediate treatment.

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When to see a vet urgently

A sudden neurological symptom needs urgent investigation, even if you do not know whether a stroke is responsible:

  • your cat falls over or cannot get up and walk;
  • sight is lost suddenly or your cat seems severely confused;
  • your cat has seizures, collapses or loses consciousness.

Find an emergency vet. Do not wait at home for a definite diagnosis based on the symptoms.

Overview

In an ischaemic stroke, blood flow through an artery in the brain is blocked by a thrombus or embolus. Nerve cells die rapidly from lack of oxygen, and the cat develops sudden neurological signs. Unlike epilepsy or tumours, a stroke develops suddenly in an animal that appears outwardly normal.

A sudden onset fits a cerebrovascular problem, but does not distinguish it from every other disease. Another neurological problem may also become noticeable to an owner suddenly. A vestibular disorder, for example, can cause a very rapidly developing head tilt and falling. Epilepsy, a tumour or inflammation therefore cannot be ruled out solely by the way symptoms begin.

Ischaemic injury means tissue damage resulting from blocked blood flow. It differs from a haemorrhagic stroke, in which a blood vessel leaks into brain tissue. Both can cause similar symptoms, but their underlying causes and treatment needs differ. Symptom severity also depends on which part of the brain is affected, rather than just the size of the damaged area.

Causes

Important factors that may lead to stroke in cats include:

  • thromboembolism associated with heart disease, particularly hypertrophic cardiomyopathy (HCM);
  • high arterial blood pressure;
  • chronic kidney disease;
  • diabetes;
  • hyperthyroidism;
  • inflammatory or infectious diseases, including toxoplasmosis and viral diseases;
  • tumours or metastases that disrupt blood flow through vessels.

An underlying disease promoting clot formation may be found, but the link is not clear in every case. Changes in blood flow, blood composition and the tendency to clot can affect coagulation. Material travelling through a vessel other than a blood clot can also cause a blockage. Investigations therefore look for inflammation and tumours as well as heart disease.

Risk factors

Stroke risk is higher in cats that:

  • are elderly;
  • have heart disease, particularly HCM;
  • have high blood pressure;
  • have chronic kidney disease;
  • have endocrine disorders, such as hyperthyroidism or diabetes.

There is little research on risk factors for strokes in cats. A concurrent disease does not automatically mean that it caused the stroke. In a small study of nine cats, several had heart disease, but mild heart muscle thickening without left atrial enlargement was considered a possible incidental finding in some cases. An individual heart finding must therefore be interpreted alongside the rest of the investigation.

Strokes have also been described in young adult cats. No particular predisposed breed has been established. Older age increases the likelihood of many underlying diseases, but a sudden change in a young cat's ability to function also needs investigation.

Symptoms

Clinical signs depend on the affected area of the brain:

  • sudden loss of coordination and an unsteady gait;
  • a head tilt or circling;
  • sudden blindness;
  • seizures;
  • paralysis or limb weakness;
  • behavioural changes and disorientation;
  • loss of consciousness in severe cases.

A balance disturbance may include nystagmus, involuntary back-and-forth eye movements. Your cat may tilt their head and fall to the same side. Similar signs can arise from disease of the inner ear's balance organ or the brain. These cannot be reliably distinguished at home, and the symptoms do not justify a promise that the condition is harmless.

High blood pressure can also cause confusion, behavioural changes, balance difficulties or seizures. Sudden blindness, meanwhile, may be caused by retinal damage in the eye rather than a brain infarction. Eye examination and blood pressure measurement are therefore often part of investigating a cat that suddenly loses sight.

Complications and consequences

An ischaemic stroke can lead to:

  • permanent neurological deficits, including paralysis or blindness;
  • repeated strokes;
  • reduced quality of life;
  • death with severe brain damage.

Severe initial symptoms do not always mean that a cat cannot recover. Equally, early improvement alone does not establish the long-term prognosis. In a small feline study, short-term outcomes were often favourable, but long-term follow-up was insufficient for firm conclusions. Prognosis considers the severity of any heart disease, tumour or other underlying illness as well as neurological injury.

Diagnosis at the vet

Investigations used to confirm a stroke include:

  • a neurological examination;
  • blood tests to rule out metabolic causes;
  • blood pressure measurement;
  • an ECG and heart ultrasound to look for heart disease;
  • brain MRI or CT, described as the gold standard for distinguishing stroke from a tumour or inflammation.

Why are several investigations needed?

At the appointment, explain as precisely as possible when your cat was last normal and how symptoms changed afterwards. Mention medicines given, possible injuries and exposure to poisons. The word episode can mean falling over, loss of consciousness or an actual seizure to an owner. Describing the event helps distinguish these and choose investigations.

The neurological examination separately assesses consciousness, behaviour, head position, eye function and movement. Staggering is not the same as loss of muscle strength, although both can occur together. A head tilt and turning the head to one side are also different findings. The examination is adapted to your cat's condition, because not every test can be performed safely or interpreted reliably in an unconscious or sedated animal.

The neurological examination helps locate the problem within the nervous system. Brain MRI is particularly useful when assessing a suspected stroke. The location of changes is compared with the areas supplied by blood vessels, and different imaging techniques also help assess the possibility of bleeding. MRI and CT, listed above, are therefore not equivalent investigations in every situation.

Blood tests do not confirm a brain infarction on their own. They look for metabolic disturbances, for example, and assess other aspects of health. Blood clotting, urine and the possibility of infectious diseases are investigated if needed. A cerebrospinal fluid sample may be considered to investigate other central nervous system diseases. The order of tests is chosen according to your cat's condition and imaging findings.

Blood pressure is measured with a suitable cuff and the result checked through repeated measurements. Vigorous movement or restraint can distort a reading. If blood pressure remains high, associated diseases such as kidney disease or hyperthyroidism are also sought. A single measurement does not reveal the type of brain injury.

Treatment and rehabilitation

Treatment addresses the underlying disease identified and your cat's immediate needs. Clot-dissolving medicines used in people have not become an established treatment for feline stroke. Do not start medication affecting blood clotting on your own initiative. Distinguishing ischaemic from haemorrhagic disease and considering other illnesses are the vet's responsibility.

In hospital, care may support fluid intake and nutrition and maintain bladder function. If your cat cannot change position, staff help reposition them to prevent pressure injuries. Physiotherapy is used if needed, and brain swelling is treated according to the findings. Not every cat needs the same supportive measures.

Function may begin to return over days and continue improving over weeks. Neurological deficits may remain, with varying effects on everyday life. Rehabilitation is tailored to whether your cat can walk, eat, drink and manage toileting. Recovery speed is not inferred from another animal's recovery time.

A cat going home while still unsteady needs a safe, confined area where they cannot fall from a height or injure themselves. Agree with the treating vet what help is needed with eating and movement. If your cat worsens again, the cause is reassessed rather than the change being automatically considered normal rehabilitation.

Prevention

There is no specific prevention, but risk may be reduced through:

  • regular cardiac examinations for susceptible cats;
  • blood pressure monitoring;
  • treatment of chronic kidney disease, diabetes and hyperthyroidism;
  • an appropriate diet and maintenance of a healthy weight;
  • regular check-ups for elderly cats.

Treating underlying diseases is worthwhile but does not guarantee prevention of a stroke. Blood pressure monitoring is particularly useful for cats with kidney disease, hyperthyroidism or heart disease. High pressure can damage the eyes, kidneys and heart as well as the brain. A check-up may identify this problem before you notice a sudden symptom.

What it means for owners

Ischaemic stroke is uncommon in cats but serious. Owners should remember that sudden loss of coordination, limb weakness or seizures are reasons to seek immediate assessment by a veterinary neurologist. Timely care can restore function in some animals, but the prognosis always depends on the severity of brain injury.

Note: this material provides general information and does not replace veterinary advice. If symptoms develop, contact a vet immediately.

Frequently asked questions

Does a sudden head tilt always mean a stroke?

No. An inner ear balance disorder can also begin quickly and look dramatic. Some vestibular diseases recover well, but similar symptoms can occur with serious brain disease. A sudden tilt and falling therefore need prompt investigation.

Can a cat recover from a stroke?

Yes, and some cats regain a substantial amount of their mobility. Recovery is affected by the location and severity of brain injury and concurrent diseases. Research on long-term prognosis in cats is limited, so no definite recovery time can be promised.

Is treatment needed if symptoms are already improving?

Yes. Sudden neurological symptoms need investigation even when they ease. An underlying blood pressure problem or another disease requiring treatment may be found. Visible improvement in balance does not show that the original cause has resolved.

This article is for general information only and is not a guide to treatment. If you notice the first signs of illness, contact your vet.

Paw4care editorial team

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